WASHINGTON — Kistler Aerospace Corp. will lay off the majority of its 25 employees by the end of October after its main financial benefactor opted to pull the plug on the company, which has spent over a decade and some $500 million trying to develop a reusable rocket.

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Brian Berger is editor in chief of SpaceNews.com and the SpaceNews magazine. He joined SpaceNews.com in 1998, spending his first decade with the publication covering NASA. His reporting on the 2003 Space Shuttle Columbia accident was recognized with...